USMLE Cell Injury, Cellular Death & Cancer High Yield List
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 Published On Apr 8, 2016

10 – Metastasis
8 – Free Radicals
8 – Necrosis
8 – Reversible vs. Irreversible Cell Injury
7 - Cellular Adaptions
7 – Apoptosis
5 – Amyloidosis
5 – Cell Cycle
4 – p53 Tumor Suppressor
3 - Bcl-2 Oncogene
2 – MYC Oncogene
2 – rb Tumor Suppressor
1 – HER2/Neu Oncogene
1 – E6 & E7 Oncogenes
1 – BRCA 1 & 2 Tumor Suppressor

Low Yield/No Yield:
Other Oncogenes (Ras, Ret, Ki-67, C-Kit …)
Other Tumor Suppressors (APC, DCC, NF-2…)
Telomeres
Epidemiology of which cancers are most common
Pyknosis/Karyorrhexis/Karyolsis
Fibrinoid Necrosis
Psommoma Bodies
Fenton Reaction
Creation of free radicals by ionizing radiation
Dialysis associated amyloid
Amylin Amyloid in diabetes
TNM system & How to determine specific grade/stage

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