Illustrated is the power of combined interference with different DNA damage response processes to combat cancer: Homologous recombination, which is selectively deficient in the tumour due to the BRCA defect, and base excision repair of single strand breaks, which is blocked by the administration of PARP inhibitors.

Client:
Dr. Rini de Crom
Dr. Marja Miedema
www.erasmusmc.nl, 2014

www.ddresponse.eu/

Funded by the 7th Framework Programme of the European Commission in the theme Health.

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