Making an Old Pain Medication (Acetanilide)
Apoptosis Apoptosis
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 Published On Apr 28, 2024

In this video I make the old pain medication acetanilide (brand name Antifebrin) from some aniline I made in a previous video.
This is technically an intermediate step in a long process I'm working on to make some Azo dyes, which require para-nitroaniline as a reagent. Acetanilide is required to make para-nitroaniline, as the acetylation of the amine prevents meta-substitution.

PS: The thumbnail image is a picture of acetanilide crystals under polarized light microscopy.
Stock photo by: by Karl Gaff on the Science Photo Library

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