Welcome to MsMojo, and today we’re counting down our picks for the times Missy shone as Sheldon’s sister on “Young Sheldon” and the times Penny took on that role in “The Big Bang Theory.” Our countdown includes Sheldon opens up to her, giving Sheldon the talk, hugging Sheldon when he cries, and more! Which brother-sister bond was YOUR favorite? Let us know in the comments.

Watch more great "Bang Bang" videos here:
Top 10 Times Missy Was the Best Character on Young Sheldon -    • Top 10 Times Missy Was the Best Chara...  
Top 10 Times Missy Was a Savage on Young Sheldon -    • Top 10 Times Missy Was a Savage on Yo...  
Top 20 Penny & Sheldon Moments on The Big Bang Theory -    • Top 20 Penny & Sheldon Moments on The...  

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