This video talks about Nucleotide excision repair (NER) which is a DNA repair mechanism. Cells use nucleotide excision repair to fix DNA regions containing chemically modified bases, often called chemical adducts, that distort the normal shape of DNA locally . Mutation in XP family genes leads to defect in nucleotide excision repair and are involved in Xeroderma pigmentosum (XP) . Nucleotide excision repair is a well conserved DNA repair mechanism which is transcription coupled.



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