Mithradates was a leader known by a Persian name meaning “sent by Mithras”, the ancient Persian sun god. Descended from the Persian royal dynasty and a descendant of Alexander the Great, Mithradates saw himself as the unifier of East and West and the defender of the East against Roman domination. A man of superior intellect and fiery ambition, Mithradates bravely resisted the Roman Republic. His father was poisoned to death, but Mithradates survived several poisoning attempts and developed immunity by experimenting with poisons. After his death, Mithradates' potion was used by many people, from Roman emperors to Chinese high officials. Mithradates was also a patron of science and the arts, making significant advances in military engineering and is believed to have been the author of the Antikythera device, the world's first computer. Mithradates' goal was to unite the West and the East and establish a great Black Sea empire. The Romans, despite their best generals, could not cope with him and could not “tame” him. Mithradates became a legend in his own time and was recognized as Rome's greatest enemy. As a Persian leader who idealized democratic Greece, he saw Rome as barbaric and dreamed of uniting Greek and Eastern cultures. Mithradates was a brave warrior, strategist, poison scholar, scientific researcher, lover and art enthusiast. Under his leadership, the Wars of Mithradates made even Rome appreciate its most implacable enemy. In 88 BC, a revolt against Rome took place in a number of cities in Anatolia, led by Mithradates, and thousands of Romans were slaughtered. Although the Romans had a large population among the settlers in Anatolia, Mithradates' resistance deeply affected them and created a deep hatred of Rome. Many who traded, collected taxes and built settlements for the Romans were hated by the local population and joined Mithradates' resistance. Mithradates' resistance became a symbol of an era that questioned Rome's dominance in Anatolia.

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