Which behaviors induce & suppress Autophagy? Can we have too much autophagy? Does autophagy affect cancer and aging? Two research scientists discuss common ideas on autophagy and the science behind them.

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References:
1-https://skeletalmusclejournal.biomedc...
2-https://www.ncbi.nlm.nih.gov/pmc/arti...
3-https://www.molbiolcell.org/doi/full/...
4-https://academic.oup.com/nutritionrev...
5-https://onlinelibrary.wiley.com/doi/a...
6-https://www.nature.com/articles/cr201...
7-https://www.ncbi.nlm.nih.gov/pmc/arti...
8-https://www.ncbi.nlm.nih.gov/pmc/arti... IF & CR cause autophagy
https://www.sciencedirect.com/science...
9-https://www.ncbi.nlm.nih.gov/pmc/arti...
10-https://www.mdpi.com/2073-4409/8/2/123
11-https://www.sciencedirect.com/science... ox stress
12-https://www.mdpi.com/2072-6694/13/3/533
https://www.ncbi.nlm.nih.gov/pmc/arti...
13-https://pubmed.ncbi.nlm.nih.gov/17018... autophagy & cancer effect varies
14-https://www.mdpi.com/2072-6694/13/14/...
15-https://aacrjournals.org/cancerdiscov... chemotherapy
16-https://www.ncbi.nlm.nih.gov/pmc/arti...
17-https://www.sciencedirect.com/science... 17-19h fasting
18-https://www.mdpi.com/2072-6643/11/6/1234 18h
19-https://www.ncbi.nlm.nih.gov/pmc/arti... 72h water fasting
20-https://www.tandfonline.com/doi/abs/1... nematode lifespan
21-https://www.nature.com/articles/s4358... autophagy decreases w age
22-https://www.sciencedirect.com/science... lysosome w age
23-https://journals.sagepub.com/doi/abs/... exercise & glutathione
24-https://www.ncbi.nlm.nih.gov/pmc/arti... 72h fasting loss little muscle
25-https://pubmed.ncbi.nlm.nih.gov/37377...

Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.

#NutritionMadeSimple #GilCarvalho

0:00 Sneak preview
0:40 Intro
1:44 What is autophagy
4:53 Turning Autophagy ON & OFF
6:49 Exercise and autophagy
8:16 Fasting vs calorie restriction
9:08 Triggers of autophagy
10:53 Autophagy and cancer
13:26 Autophagy nuances
16:13 Timing of Autophagy induction
21:19 Humans vs lab animals
24:44 Measuring Autophagy
27:03 Autophagy & Aging
30:48 Autophagy & muscle loss
32:20 Summary & takeaways